Question: How Does Hypertonic Saline Work?

What is hypertonic saline used for?

Historically, therapy with hypertonic saline was widely used for a variety of conditions.

Currently, there are 3 primary indications for its use in critical care: hyponatremia, volume resuscitation, and brain injury..

How does nebulized hypertonic saline work?

It works by increasing the amount of sodium (salt) in the airways. Salt attracts water into the airways, which thins the mucus, making it easier to cough out. Research has shown that inhaling hypertonic saline twice a day helps people with cystic fibrosis experience fewer lung infections.

Does hypertonic saline increase blood pressure?

Despite reports of initial hypotension with the rapid infusion of hypertonic saline solutions, the evidence shows that, overall, they may be of benefit in shock states [37]. Of the eleven trials focussing on trauma, single boluses of hypertonic saline were shown to increase blood pressure in six of these [38-43].

What is 3% saline used for?

3% and 5% Sodium Chloride Injection, USP is a sterile, nonpyrogenic, hypertonic solution for fluid and electrolyte replenishment in single dose containers for intravenous administration. The pH may have been adjusted with hydrochloric acid. It contains no antimicrobial agents.

Is isotonic or hypertonic better?

Scientific evidence has proven that when the salt comes in contact with your sinuses, it draws out the mucus and fluid more effectively than an isotonic saline would. Since hypertonic solutions are stronger than isotonic, they should be your go-to, particularly if your sinuses are more swollen than normal.